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The aim is to give an introduction to new developments at the interface of Mathematics and Biology.
To achieve this goal three mini-courses of four hours each will be given by three experts in the field, whereas applications will be illustrated by scientists who are working in the field. The focuss will be on different fields of mathematics playing a role in biological and biochemical research.
The Winterschool is organized for anyone wishing to get acquainted with the mathematical problems, challenges and achievements in the field of biology and medicine. We hope to attract PhD-students and researchers interested to start working in this field.
A special target group is formed by undergraduate students in the final phase of their studies in Mathematics, Computer Science, Bio-informatics or Theoretical Biology. The participation of of undergraduate students will be stimulated by asking universities to give credit for participation, and by offering a number of grants, for which any qualified student can apply. For these grants we have acquired funding from scientific institutions and industry.
There will be an opportunity to discuss the potential research possibilities and limitations. Discussion in the poster session will be stimulated.
The second main speaker of a four mini-course is Professor
Peter Clote
(Boston) who will address the topic: Macromolecules:
Aspects of biology and structure prediction. Relevant parts of a
book by Professor Clote can be
downloaded here.
The third main speaker of a four hour mini-course is
Professor
David Balding (London) who will give a series of four
loosely-connected lectures on statistical problems, and computational
solutions, involved in making sense of genetic data from samples of
individuals outline in pdf. The lecture notes
can be downloaded here.
The following speakers have accepted to present a lecture devoted to
applications:
Jan Pieter Abrahams (Leiden Institute of Chemistry, UL)
Nicola Armstrong (EURANDOM, Eindhoven)
Albert Goldbeter (Faculte' des Sciences, Universite' Libre de
Bruxelles)
Jan van de Greef (TNO Pharma Zeist)
Paulien Hogeweg (Bioinformatics group, Utrecht University)
Jaap Kaandorp (Faculty of Science, University of Amsterdam)
Mark Peletier (CWI, Amsterdam)
Erik De Schutter (Born-Bunge Foundation, University of Antwerp)
Detailed Programme
Monday 15 december 2003
9.30-10.25 Arrival
10.25-10.30 Welcome and opening
10.30-11.25 Peter Clote
Macromolecules I: Aspects of biology
and structure prediction
11.30-12.25 Peter Clote
Macromolecules I: Aspects of biology
and structure prediction
12.30-13.30 Lunch
15.00-15.35 Erik de Schutter
Computational neuroscience: from
channels to behavior
15.35-16.10 Jan van de Greef
Systems Biology, a new discovery strategy in Life Sciences :
a challenge for computational biology
16.10-16.30 Tea
16.30-17.25 Hans Othmer
An introduction to mathematical modeling of
signal transduction and gene control networks I
17.30-18.25 Hans Othmer
An introduction to mathematical modeling of
signal transduction and gene control networks I
19.00 Dinner
Tuesday December 16
9.00-9.55 David Balding
The problem of genetic data: introduction to coalescent theory and
approximate computation methods
10.00-10.55 David Balding
Applications of computational coalescent theory in conservation
genetics and human disease-gene mapping
11.00-11.15 Coffee
11.15-11.50 Nicola Armstrong
Statistics and microarrays: an illustrative example
11.50-12.25 Mark Peletier
Diffusion in MCA: Adding
space to cells
12.30-13.30 Lunch
15.00-15.35 Jan Pieter Abrahams
Eroded functions: evolution of the predictability of life
15.35-16.10 Paulien Hogeweg
Generegulation and Evolution
16.10-16.30 Tea
16.30-17.25 Peter Clote
Macromolecules II: Aspects of biology
and structure prediction
17.30-18.30 Peter Clote
Macromolecules II: Aspects of biology
and structure prediction
19.00 Dinner
Wednesday December 17
9.00-9.55 Hans Othmer
An introduction to mathematical modeling of
signal transduction and gene control networks II
10.00-10.55 Hans Othmer
An introduction to mathematical modeling of
signal transduction and gene control networks II
11.00-11.15 Coffee
11.15-11.50 Jaap Kaandorp
Modelling the formation of a bodyplan in metazoans (animals)
11.50-12.25 Albert Goldbeter
Mathematical modeling of circadian rhythms
12.30-13.30 Lunch
14.00-14.55 David Balding
Inferring haplotype from genotype data
15.00-15.55 David Balding
Detecting adaptive selection
16.00 Closing
Date and place
The winterschool starts at 09.30 on December 15th,
2003 in the
Congress Centre 'De Wageningse Berg',
6703 DS Wageningen
(tel. +31 317 495911, fax +31 317 418208).
Participants travelling by train are advised to take
a train taxi from the Ede/Wageningen railway station. Between 9.30 and 10.00
o'clock traintaxis will be expecting participants of the meeting. Another
possibility is taking the bus from railway station Ede-Wageningen. The buses
run every half hour and one has the following options. The first option is
the interliner 336 (direction Arnhem) leaving the station at 9:17. Take the
busstop `Diedenweg' (arrival 9:37) and walk for 15 minutes to the conference
side (see the map). The second option the bus 86
(direction Arnhem) leaving the station at 9:10. Take the busstop
`Wageningse Berg' (arrival 9:34) and walk for 5 minutes to the conference
side (see the map, but note that the number of
the bus on the map is not correct).
![[map of the Netherlands]](nl-big.gif)
![[map of the region]](reg-mid.gif)
For further details click on map of the Generaal Foulkeslaan. For additional regional maps click on map of Wageningen or map of Wageningen details.
All applicants should use the Application Form (registration closed). Students who apply for support should in addition send a letter containing a short motivation to
Prof. dr. Ritsert C. Jansen
Institute of Mathematics and Computing Science (IWI) PO Box 800 9700 AV GroningenThe closing date for applications is 30 November 2003, but candidates are recommended to apply as soon as possible since the number of participants is limited.
List of registrated participants.
De deelnemerskosten (zie de `application form') dienen over te worden
gemaakt op bankrekening nr. 31.35.57.977 van de
St. W.I.C.
Postbus 94079
1090 GB Amsterdam
bij de RABO bank te Amsterdam onder vermelding van uw naam
en van `WS-MB-2003'.
Participants who wish to present a poster have to submit an abstract with their registration form before November 15st.
Mathisca de Gunst (VUA) degunst@cs.vu.nl
Leen Stougie (CWI/TUE) Leen.Stougie@cwi.nl
Sjoerd Verduyn Lunel (UL) verduyn@math.leidenuniv.nl
Maintained by: verduyn@math.leidenuniv.nl
Last modified: Friday, 19 December-2003
